Monday, August 6, 2012

Tussizone-12 RF


Pronunciation: car-beta-PEN-tane/klor-fen-EER-a-meen
Generic Name: Carbetapentane/Chlorpheniramine
Brand Name: Tussi-12


Tussizone-12 RF is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


Tussizone-12 RF is an antihistamine and cough suppressant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.


Do NOT use Tussizone-12 RF if:


  • you are allergic to any ingredient in Tussizone-12 RF

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Tussizone-12 RF:


Some medical conditions may interact with Tussizone-12 RF. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat or a history of heart problems

  • if you have a history of high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid

  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Tussizone-12 RF. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Furazolidone, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Tussizone-12 RF may be increased

  • Hydantoins (eg, phenytoin) because side effects may be increased by Tussizone-12 RF

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tussizone-12 RF may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Tussizone-12 RF:


Use Tussizone-12 RF as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Tussizone-12 RF may be taken with or without food.

  • If you miss a dose of Tussizone-12 RF, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tussizone-12 RF.



Important safety information:


  • Tussizone-12 RF may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tussizone-12 RF. Using Tussizone-12 RF alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Tussizone-12 RF without checking with your doctor.

  • Tussizone-12 RF contains chlorpheniramine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains chlorpheniramine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Tussizone-12 RF for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Tussizone-12 RF may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Tussizone-12 RF. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Tussizone-12 RF for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tussizone-12 RF.

  • Use Tussizone-12 RF with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Tussizone-12 RF in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Tussizone-12 RF, discuss with your doctor the benefits and risks of using Tussizone-12 RF during pregnancy. It is unknown if Tussizone-12 RF is excreted in breast milk. Do not breast-feed while taking Tussizone-12 RF.


Possible side effects of Tussizone-12 RF:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Tussizone-12 RF side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Tussizone-12 RF:

Store Tussizone-12 RF at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tussizone-12 RF out of the reach of children and away from pets.


General information:


  • If you have any questions about Tussizone-12 RF, please talk with your doctor, pharmacist, or other health care provider.

  • Tussizone-12 RF is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tussizone-12 RF. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tussizone-12 RF resources


  • Tussizone-12 RF Side Effects (in more detail)
  • Tussizone-12 RF Use in Pregnancy & Breastfeeding
  • Drug Images
  • Tussizone-12 RF Drug Interactions
  • Tussizone-12 RF Support Group
  • 0 Reviews for Tussizone-12 RF - Add your own review/rating


  • Tussizone-12 RF Concise Consumer Information (Cerner Multum)



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