Fiorinal with Codeine III

Pronunciation: AS-pir-in/bue-TAL-bi-tal/KAF-een/KOE-deen
Generic Name: Aspirin/Butalbital/Caffeine/Codeine
Brand Name: Examples include Ascomp-Codeine and Fiorinal with Codeine

Fiorinal with Codeine III is used for:

Treating tension headaches. It may also be used for other conditions as determined by your doctor.

Fiorinal with Codeine III is a salicylate, barbiturate, caffeine, and narcotic combination. How these medicines work is not completely understood. Aspirin reduces pain and inflammation. Caffeine may work by constricting blood vessels that may cause headaches. Butalbital has a depressant effect that reduces anxiety and causes relaxation. Codeine works in the central nervous system to decrease pain.

Do NOT use Fiorinal with Codeine III if:

• you are allergic to nonsteroidal anti-inflammatory drugs (NSAIDs), any ingredient in Fiorinal with Codeine III, or any other codeine- or morphine-related medicine (eg, oxycodone).


• you have von Willebrand disease, the blood disease porphyria, severe stomach or intestinal problems (eg, peptic ulcer, pseudomembranous colitis), blood clotting problems (eg, hemophilia), severe bleeding, severe liver damage, or severe low levels of vitamin K


• you are taking sodium oxybate (GHB)


• you are a child or teenager that has the flu, chickenpox, or joint problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fiorinal with Codeine III:

Some medical conditions may interact with Fiorinal with Codeine III. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have asthma, stomach or intestinal problems (eg, inflammatory bowel disease), liver problems, the flu, nasal polyps, kidney problems, lung or respiratory tract disease, an enlarged prostate, severe heart disease, difficulty urinating, chickenpox, underactive thyroid, or vitamin K deficiency


• if you are in very poor health or have a history of stroke, anxiety, substance abuse or dependence, depression, or suicidal thoughts or behaviors


• if you have had head trauma, growths in the brain, or stomach or intestinal surgery

Some MEDICINES MAY INTERACT with Fiorinal with Codeine III. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg warfarin), celecoxib, clopidogrel, heparin, or NSAIDs (eg, ibuprofen) because the risk of serious side effects, such as stomach ulcers and bleeding, may be increased


• Benzodiazepines (eg, chlordiazepoxide), cimetidine, HIV protease inhibitors (eg, ritonavir), monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), narcotic analgesics (eg, morphine), sleeping medicines (eg, temazepam), or sodium oxybate (GHB) because they may increase the risk of Fiorinal with Codeine III's side effects


• Naltrexone because it may decrease Fiorinal with Codeine III's effectiveness


• Carbonic anhydrase inhibitors (eg, acetazolamide), insulin, meglitinides (eg, repaglinide), methotrexate, quinolone antibiotics (eg, ciprofloxacin), or valproic acid because the risk of their side effects may be increased by Fiorinal with Codeine III


• Angiotensin-converting enzyme (ACE) inhibitors (eg, lisinopril), antipsychotics (eg, clozapine), beta-blockers (eg, atenolol), corticosteroids (eg, prednisone), doxycycline, estrogens (eg, estradiol), metronidazole, oral contraceptives (eg, norethindrone/ethinyl estradiol), probenecid, quinidine, sulfinpyrazone, theophylline, or tricyclic antidepressants (eg, amitriptyline) because their effectiveness may be decreased by Fiorinal with Codeine III

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fiorinal with Codeine III may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fiorinal with Codeine III:

Use Fiorinal with Codeine III as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Fiorinal with Codeine III by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.


• If you miss a dose of Fiorinal with Codeine III and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Fiorinal with Codeine III.

Important safety information:

• Fiorinal with Codeine III may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Fiorinal with Codeine III with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Fiorinal with Codeine III; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Serious stomach ulcers or bleeding can occur with the use of Fiorinal with Codeine III. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Fiorinal with Codeine III with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.


• Tell your doctor or dentist that you take Fiorinal with Codeine III before you receive any medical or dental care, emergency care, or surgery.


• Fiorinal with Codeine III has aspirin in it. Before you start any new medicine, check the label to see if it has aspirin in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Taking more than the recommended dose or taking Fiorinal with Codeine III for longer than prescribed may be habit-forming.


• Aspirin has been linked to a serious illness called Reye syndrome. Do not give Fiorinal with Codeine III to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.


• Hormonal birth control (eg, birth control pills) may not work as well while you are using Fiorinal with Codeine III. To prevent pregnancy, use an extra form of birth control (eg, condoms).


• Use Fiorinal with Codeine III with caution in the ELDERLY; they may be more sensitive to its effects.


• Fiorinal with Codeine III should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fiorinal with Codeine III while you are pregnant. Fiorinal with Codeine III is not recommended during the last 6 months (second and third trimesters) of pregnancy because it may cause harm to the fetus. Fiorinal with Codeine III is found in breast milk. If you are or will be breast-feeding while you use Fiorinal with Codeine III, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, Fiorinal with Codeine III may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Fiorinal with Codeine III stops working well. Do not take more than prescribed.

Some people who use Fiorinal with Codeine III for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you suddenly stop taking Fiorinal with Codeine III, you may experience WITHDRAWAL symptoms, including anxiety, dizziness, hallucinations, lightheadedness, muscle twitching, nausea, seizures, sleeplessness, trembling hands and fingers, vomiting, or weakness.

Possible side effects of Fiorinal with Codeine III:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; gas; indigestion; lightheadedness; nausea; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; severe drowsiness; shallow breathing; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Fiorinal with Codeine III side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; constriction of the pupils; fast or irregular heartbeat; loss of consciousness; nausea; ringing in the ears; sleeplessness; slow or shallow breathing; stomach pain; tremor; unusual drowsiness or dizziness; vomiting.

Proper storage of Fiorinal with Codeine III:

Store Fiorinal with Codeine III at room temperature, below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Fiorinal with Codeine III out of the reach of children and away from pets.

General information:

• If you have any questions about Fiorinal with Codeine III, please talk with your doctor, pharmacist, or other health care provider.


• Fiorinal with Codeine III is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Fiorinal with Codeine III. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Fiorinal with Codeine III resources

• Fiorinal with Codeine III Side Effects (in more detail)
• Fiorinal with Codeine III Use in Pregnancy & Breastfeeding
• Fiorinal with Codeine III Drug Interactions
• Fiorinal with Codeine III Support Group
• 4 Reviews for Fiorinal with Codeine III - Add your own review/rating

Compare Fiorinal with Codeine III with other medications

• Headache

Sinarest

Generic Name: acetaminophen, chlorpheniramine, and pseudoephedrine (a seet a MIN oh fen, klor fen IR a meen, soo doe e FED rin)

Brand Names: Alka-Seltzer Plus Cold Liquigel, Allerest Headache Strength, Allerest Sinus, Cold Medicine Plus, Comtrex Allergy Sinus, Comtrex Allergy Sinus Maximum Strength, Comtrex Allergy Sinus Night and Day, Kolephrin, Sinarest, Sinutab Ex-Strength, Theraflu Cold & Sore Throat (pseudoephedrine), Theraflu Flu & Sore Throat (pseudoephedrine), Theraflu Maximum Strength

What is Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, chlorpheniramine, and pseudoephedrine is used to treat headache, fever, body aches, runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Acetaminophen, chlorpheniramine, and pseudoephedrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine)?

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen and can increase certain side effects of chlorpheniramine. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose.

What should I discuss with my healthcare provider before taking Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine)?

You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

• 
  

  liver disease, cirrhosis, or a history of alcoholism;

  
  


• 
  

  a blockage in your digestive tract (stomach or intestines);

  
  


• 
  

  diabetes;

  
  


• 
  

  kidney disease;

  
  


• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;

  
  


• 
  

  enlarged prostate or urination problems;

  
  


• 
  

  low blood pressure;

  
  


• 
  

  pheochromocytoma (an adrenal gland tumor); or

  
  


• 
  

  if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

  
  

It is not known whether acetaminophen, chlorpheniramine, and pseudoephedrine will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant. This medication may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without your doctor's advice if you are breast-feeding a baby.

How should I take Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Dissolve one packet of the powder in at least 4 ounces of water. Stir this mixture and drink all of it right away.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days. Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1 800 222 1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine)?

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen, and can increase certain side effects of chlorpheniramine. This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  chest pain, rapid pulse, fast or uneven heart rate;

  
  


• 
  

  confusion, hallucinations, severe nervousness;

  
  


• 
  

  tremor, seizure (convulsions);

  
  


• 
  

  easy bruising or bleeding, unusual weakness;

  
  


• 
  

  urinating less than usual or not at all;

  
  


• 
  

  nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, uneven heartbeats, seizure).

  
  

Less serious side effects may include:

• 
  

  dizziness, drowsiness;

  
  


• 
  

  mild headache;

  
  


• 
  

  dry mouth, nose, or throat;

  
  


• 
  

  constipation;

  
  


• 
  

  blurred vision;

  
  


• 
  

  feeling nervous; or

  
  


• 
  

  sleep problems (insomnia);

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sinarest (acetaminophen, chlorpheniramine, and pseudoephedrine)?

Ask a doctor or pharmacist before using this medicine if you regularly use other medicines that make you sleepy (such as narcotic pain medication, sedatives, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine.

Tell your doctor about all other medicines you use, especially:

• 
  

  leflunomide (Arava);

  
  


• 
  

  topiramate (Topamax);

  
  


• 
  

  zonisamide (Zonegran);

  
  


• 
  

  an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;

  
  


• 
  

  an antidepressant;

  
  


• 
  

  birth control pills or hormone replacement therapy;

  
  


• 
  

  bladder or urinary medications;

  
  


• 
  

  blood pressure medication;

  
  


• 
  

  a bronchodilator;

  
  


• 
  

  cancer medicine;

  
  


• 
  

  cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;

  
  


• 
  

  gout or arthritis medications (including gold injections);

  
  


• 
  

  HIV/AIDS medication;

  
  


• 
  

  medication for nausea and vomiting, stomach ulcers, or irritable bowel syndrome;

  
  


• 
  

  medicines to treat psychiatric disorders;

  
  


• 
  

  an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or

  
  


• 
  

  seizure medication.

  
  

This list is not complete and other drugs may interact with acetaminophen, chlorpheniramine, and pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Sinarest resources

• Sinarest Use in Pregnancy & Breastfeeding
• Sinarest Drug Interactions
• Sinarest Support Group
• 0 Reviews for Sinarest - Add your own review/rating

• Children's Tylenol Cold Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Sinarest with other medications

• Cold Symptoms
• Hay Fever

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, chlorpheniramine, and pseudoephedrine.

carmustine

Generic Name: carmustine (kar MUS teen)

Brand Names: BiCNU, Gliadel

What is carmustine?

Carmustine is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Carmustine is used to treat brain tumors, Hodgkin's disease, multiple myeloma, and non-Hodgkin's lymphoma.

Carmustine is sometimes given with other cancer medications.

Carmustine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about carmustine?

Do not use carmustine if you are pregnant. It could harm the unborn baby. You should not use this medication if you are allergic to carmustine.

Before receiving carmustine, tell your doctor if you have bone marrow suppression, liver or kidney disease, or a history of lung or breathing problems.

Carmustine is usually given once every 6 weeks. You may be given either a single injection or multiple injections over a 2-day period. Follow your doctor's dosing instructions very carefully.

Carmustine can cause nausea and vomiting that may last up to 6 hours after your injection. Carmustine can lower blood cells that help your body fight infections. Your blood will need to be tested weekly for at least 6 weeks after you receive a dose of carmustine. Your kidneys, liver, and lung function may also need to be tested. Do not miss any follow-up visits to your doctor.

What should I discuss with my healthcare provider before receiving carmustine?

You should not receive this medication if you are allergic to it.

To make sure you can safely receive carmustine, tell your doctor if you have any of these other conditions:

• 
  

  bone marrow suppression;

  
  


• liver disease;


• kidney disease; or


• 
  

  a history of lung or breathing problems.

  
  

FDA pregnancy category D. Do not use carmustine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. It is not known whether carmustine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are being treated with carmustine.

How is carmustine given?

Carmustine is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Carmustine must be given slowly, and the IV infusion can take at least 2 hours to complete.

Carmustine is usually given once every 6 weeks. You may be given either a single injection or multiple injections over a 2-day period. Follow your doctor's dosing instructions very carefully.

Tell your caregivers if you feel any burning or pain around the IV needle when carmustine is injected. Carmustine can cause nausea and vomiting that may last up to 6 hours after your injection. You may be given anti-nausea medications to help prevent these side effects.

Carmustine can lower blood cells that help your body fight infections. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.

To be sure your blood cells do not get too low, your blood will need to be tested weekly for at least 6 weeks after you receive a dose of carmustine. This medication can have long-lasting effects on your body. Your kidneys, liver, and lung function may also need to be tested. Do not miss any follow-up visits to your doctor for blood or urine tests.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your carmustine injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of the serious side effects listed in this medication guide.

What should I avoid while receiving carmustine?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Carmustine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  new or worsening cough, fever, trouble breathing;

  
  


• 
  

  feeling short of breath on exertion;

  
  


• 
  

  chest discomfort, dry cough or hack;

  
  


• 
  

  feeling weak or tired, loss of appetite, rapid weight loss;

  
  


• 
  

  fever, chills, body aches, flu symptoms, sores in your mouth and throat;

  
  


• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  
  


• 
  

  pale skin, feeling light-headed, rapid heart rate, trouble concentrating;

  
  


• 
  

  urinating less than usual or not at all;

  
  


• 
  

  drowsiness, confusion, mood changes, increased thirst, swelling, weight gain, feeling short of breath;

  
  


• 
  

  severe burning, irritation, or skin changes where the injection was given; or

  
  


• 
  

  redness of your eyes or skin and severe warmth or tingling under your skin (within 2 to 4 hours after your carmustine injection).

  
  

Less serious side effects may include:

• 
  

  nausea, vomiting;

  
  


• 
  

  headache; or

  
  


• 
  

  mild pain, swelling, redness, or darkened skin color where the injection was given.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Carmustine Dosing Information

Usual Adult Dose for Brain/Intracranial Tumor:

For use as a single agent in previously untreated patients: 150 to 200 mg/m2 IV every 6 weeks. This dose can be given as a single or divided daily injections (75 to 100 mg/m2 on two successive days). When used with other myelosuppressive drugs or in patients in whom bone marrow reserve is depleted, doses should be adjusted accordingly. A repeat course should not be administered until platelets are >100,000/mm3 and leukocytes are >4,000/mm3. An adequate number of neutrophils should be present on a peripheral blood smear. Blood counts should be monitored weekly. Repeat courses should not be administered before 6 weeks because of delayed and cumulative toxicity.

Usual Adult Dose for non-Hodgkin's Lymphoma:

For use as a single agent in previously untreated patients: 150 to 200 mg/m2 IV every 6 weeks. This dose can be given as a single or divided daily injections (75 to 100 mg/m2 on two successive days). When used with other myelosuppressive drugs or in patients in whom bone marrow reserve is depleted, doses should be adjusted accordingly. A repeat course should not be administered until platelets are >100,000/mm3 and leukocytes are >4,000/mm3. An adequate number of neutrophils should be present on a peripheral blood smear. Blood counts should be monitored weekly. Repeat courses should not be administered before 6 weeks because of delayed and cumulative toxicity.

Usual Adult Dose for Hodgkin's Disease:

For use as a single agent in previously untreated patients: 150 to 200 mg/m2 IV every 6 weeks. This dose can be given as a single or divided daily injections (75 to 100 mg/m2 on two successive days). When used with other myelosuppressive drugs or in patients in whom bone marrow reserve is depleted, doses should be adjusted accordingly. A repeat course should not be administered until platelets are >100,000/mm3 and leukocytes are >4,000/mm3. An adequate number of neutrophils should be present on a peripheral blood smear. Blood counts should be monitored weekly. Repeat courses should not be administered before 6 weeks because of delayed and cumulative toxicity.

Usual Adult Dose for Multiple Myeloma:

For use as a single agent in previously untreated patients: 150 to 200 mg/m2 IV every 6 weeks. This dose can be given as a single or divided daily injections (75 to 100 mg/m2 on two successive days). When used with other myelosuppressive drugs or in patients in whom bone marrow reserve is depleted, doses should be adjusted accordingly. A repeat course should not be administered until platelets are >100,000/mm3 and leukocytes are >4,000/mm3. An adequate number of neutrophils should be present on a peripheral blood smear. Blood counts should be monitored weekly. Repeat courses should not be administered before 6 weeks because of delayed and cumulative toxicity.

Usual Adult Dose for Glioblastoma Multiforme:

polifeprosan 20 with carmustine implant (brand name = Gliadel Wafer):
Each wafer contains 7.7 mg of carmustine, resulting in a dose of 61.6 mg when eight wafers are implanted. It is recommended that eight wafers be placed in the resection cavity if the size and shape of it allows. Should the size and shape not accommodate eight wafers, the maximum number of wafers as allowed should be placed. Since there is no clinical experience, no more than eight wafers should be used per surgical procedure.

Usual Adult Dose for Malignant Glioma:

polifeprosan 20 with carmustine implant (brand name = Gliadel Wafer):
Each wafer contains 7.7 mg of carmustine, resulting in a dose of 61.6 mg when eight wafers are implanted. It is recommended that eight wafers be placed in the resection cavity if the size and shape of it allows. Should the size and shape not accommodate eight wafers, the maximum number of wafers as allowed should be placed. Since there is no clinical experience, no more than eight wafers should be used per surgical procedure.

What other drugs will affect carmustine?

Tell your doctor about all other medications you use, especially cimetidine (Tagamet).

There may be other drugs that can interact with carmustine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More carmustine resources

• Carmustine Side Effects (in more detail)
• Carmustine Use in Pregnancy & Breastfeeding
• Carmustine Drug Interactions
• Carmustine Support Group
• 0 Reviews for Carmustine - Add your own review/rating

• carmustine Implantation Advanced Consumer (Micromedex) - Includes Dosage Information


• Carmustine Professional Patient Advice (Wolters Kluwer)


• Carmustine MedFacts Consumer Leaflet (Wolters Kluwer)


• Carmustine Monograph (AHFS DI)


• BiCNU Prescribing Information (FDA)


• Bicnu Advanced Consumer (Micromedex) - Includes Dosage Information


• Gliadel Prescribing Information (FDA)


• Gliadel Implant Wafer MedFacts Consumer Leaflet (Wolters Kluwer)

Compare carmustine with other medications

• Brain Tumor
• Glioblastoma Multiforme
• Hodgkin's Lymphoma
• Malignant Glioma
• Multiple Myeloma
• Non-Hodgkin's Lymphoma

Where can I get more information?

• Your doctor or pharmacist can provide more information about carmustine.

See also: carmustine side effects (in more detail)

Visine Tears

Generic Name: ocular lubricant (OK yoo lar LOO bri kant)

Brand Names: Artificial Tears, Celluvisc, Clear Eyes CLR, Comfort Tears, Dry Eye Relief, GenTeal, Isopto Tears, Lacri-Lube S.O.P., Lacrisert, Lubricant Eye Drops, Moisture Drops, Oasis Tears, Opti-Free Rewetting Drops, optive, Refresh, Soothe, Sterilube, Systane, Systane Balance, Tears Again, Tears Naturale, Tears Renew, TheraTears, Ultra Fresh, Visine Tears

What is Visine Tears (ocular lubricant)?

There are many brands and forms of ocular lubricant available and not all are listed on this leaflet.

Ocular lubricant is a solution specially formulated to moisten the eyes.

Ocular lubricant is used to relieve burning, irritation, and discomfort caused by dry eyes.

Ocular lubricant may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Visine Tears (ocular lubricant)?

There are many brands and forms of ocular lubricant available and not all are listed on this leaflet.

You should not use an ocular lubricant if you are allergic to it. Ocular lubricant will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have any type of infection in your eye.

Do not allow the dropper or tube tip to touch any surface, including the eyes or hands. If the dropper or tube becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Stop using ocular lubricant and call your doctor if you have severe burning, stinging, irritation, eye pain, or vision changes.

This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Talk with your doctor if your symptoms do not improve or if they get worse while you are using ocular lubricant.

What should I discuss with my healthcare provider before using Visine Tears (ocular lubricant)?

You should not use an ocular lubricant if you are allergic to it. Ocular lubricant will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have any type of infection in your eye.

Ocular lubricant is not expected to harm an unborn baby. Ask a doctor or pharmacist about using ocular lubricant if you are pregnant. It is not known whether ocular lubricant passes into breast milk or if it could harm a nursing baby. Ask a doctor or pharmacist about using ocular lubricant if you are pregnant.

How should I use Visine Tears (ocular lubricant)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not use this medication while wearing contact lenses. Eye medication may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medication before putting your contact lenses in. Wash your hands before using ocular lubricant.

To apply the eye drops:

• 
  

  Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

  
  


• 
  

  Use only the number of drops your doctor has prescribed.

  
  


• 
  

  Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

  
  


• 
  

  Do not use the eye drops if the liquid has changed colors or has particles in it.

  
  

To apply the ointment:

• 
  

  Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip.

  
  


• 
  

  Squeeze out a ribbon of ointment 1/2-inch long into the lower eyelid pocket without touching the tip of the tube to your eye. Look down and close your eyes for a few minutes. Rolling your eyes around gently will help spread the ointment evenly.

  
  


• 
  

  After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to be able to see clearly.

  
  

Do not allow the dropper or tube tip to touch any surface, including the eyes or hands. If the dropper or tube becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Talk with your doctor if your symptoms do not improve or if they get worse while you are using ocular lubricant. Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use.

What happens if I miss a dose?

Since ocular lubricant is used on an as needed basis, you are not likely to miss a dose.

What happens if I overdose?

An overdose of ocular lubricant is not expected to be dangerous.

What should I avoid while using Visine Tears (ocular lubricant)?

This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Avoid using other medications in your eyes during treatment with ocular lubricant unless your doctor tells you to.

Visine Tears (ocular lubricant) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using ocular lubricant and call your doctor if you have a serious side effect such as:

• 
  

  severe burning, stinging, or eye irritation after using the medication;

  
  


• 
  

  eye pain; or

  
  


• 
  

  vision changes.

  
  

Less serious side effects may include:

• 
  

  mild eye burning or irritation;

  
  


• 
  

  itching or redness of your eyes;

  
  


• 
  

  watery eyes;

  
  


• 
  

  blurred vision; or

  
  


• 
  

  unpleasant taste in your mouth.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Visine Tears (ocular lubricant)?

It is not likely that other drugs you take orally or inject will have an effect on ocular lubricant used in the eyes. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Visine Tears resources

• Visine Tears Use in Pregnancy & Breastfeeding
• Visine Tears Support Group
• 0 Reviews for Visine Tears - Add your own review/rating

• FreshKote Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Genteal Advanced Consumer (Micromedex) - Includes Dosage Information


• Lacri-Lube S.O.P. Ointment MedFacts Consumer Leaflet (Wolters Kluwer)


• Lacrisert Prescribing Information (FDA)


• Lacrisert Insert MedFacts Consumer Leaflet (Wolters Kluwer)


• Lacrisert Advanced Consumer (Micromedex) - Includes Dosage Information


• Murine Tears Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Murocel Eye Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Refresh Redness Relief Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Refresh liquigel

Compare Visine Tears with other medications

• Eye Dryness/Redness

Where can I get more information?

• Your pharmacist can provide more information about ocular lubricant.

ethinyl estradiol and etonogestrel Vaginal

e-toe-noe-JES-trel, ETH-i-nil es-tra-DYE-ol

Vaginal route(Insert, Extended Release)

Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use. This risk increases with age and with heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Women who use oral contraceptives should be strongly advised not to smoke .

Commonly used brand name(s)

In the U.S.

• NuvaRing

Available Dosage Forms:

• Insert, Extended Release

Therapeutic Class: Contraceptive

Pharmacologic Class: Progestin

Uses For ethinyl estradiol and etonogestrel

The etonogestrel and ethinyl estradiol vaginal ring is a flexible combination contraceptive vaginal ring. Ethinyl estradiol is a kind of estrogen (ES-troh-jen) and etonogestrel is a kind of progesterone (proe-JES-ter-one). These are both female hormones used for contraception. The etonogestrel and ethinyl estradiol vaginal ring releases these hormones and is used to prevent pregnancy.

Etonogestrel and ethinyl estradiol vaginal ring will not protect a woman from sexually transmitted diseases (STDs), including human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) . The use of latex (rubber) condoms or abstinence (not having intercourse) is recommended for protection from these diseases.

Etonogestrel and ethinyl estradiol vaginal ring is available only from your doctor or other authorized health care professional.

Before Using ethinyl estradiol and etonogestrel

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ethinyl estradiol and etonogestrel, the following should be considered:

In deciding whether to use the combined contraceptive vaginal ring as a method of birth control, you need to consider the risks of using it as well as the good it can do. This is a decision you, your sexual partner, and your health care professional will make. For etonogestrel and ethinyl estradiol vaginal ring the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ethinyl estradiol and etonogestrel or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies with this contraceptive ring have been done only in adult patients, and it is not expected to cause different side effects in children than it does in adults. The etonogestrel and ethinyl estradiol vaginal ring is not intended for use in children or adolescents who have not yet started menstruating.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known if this works the same way in younger adults as it does in older adults. There is no specific information comparing the use of etonogestrel and ethinyl estradiol vaginal ring in the elderly with use in other age groups. The etonogestrel and ethinyl estradiol vaginal ring is not intended for use in women older than child-bearing age.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking ethinyl estradiol and etonogestrel, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using ethinyl estradiol and etonogestrel with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Boceprevir


• Felbamate


• Isotretinoin


• Paclitaxel


• Paclitaxel Protein-Bound


• Theophylline


• Tizanidine


• Tranexamic Acid

Using ethinyl estradiol and etonogestrel with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alprazolam


• Amoxicillin


• Ampicillin


• Amprenavir


• Aprepitant


• Atazanavir


• Bacampicillin


• Betamethasone


• Bexarotene


• Bosentan


• Carbamazepine


• Colesevelam


• Cyclosporine


• Darunavir


• Delavirdine


• Doxycycline


• Efavirenz


• Etravirine


• Fosamprenavir


• Fosaprepitant


• Fosphenytoin


• Ginseng


• Griseofulvin


• Lamotrigine


• Licorice


• Minocycline


• Modafinil


• Mycophenolate Mofetil


• Mycophenolic Acid


• Nelfinavir


• Nevirapine


• Oxcarbazepine


• Oxytetracycline


• Phenobarbital


• Phenytoin


• Pioglitazone


• Prednisolone


• Primidone


• Rifabutin


• Rifampin


• Rifapentine


• Ritonavir


• Roflumilast


• Rosuvastatin


• Rufinamide


• Selegiline


• St John's Wort


• Telaprevir


• Tetracycline


• Tipranavir


• Topiramate


• Troglitazone


• Troleandomycin


• Valdecoxib


• Voriconazole


• Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using ethinyl estradiol and etonogestrel with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use ethinyl estradiol and etonogestrel, or give you special instructions about the use of food, alcohol, or tobacco.

• Caffeine


• Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of ethinyl estradiol and etonogestrel. Make sure you tell your doctor if you have any other medical problems, especially:

• Abnormal or unusual vaginal bleeding (nonmenstrual)— The use of etonogestrel and ethinyl estradiol vaginal ring may delay diagnosis or worsen this condition. The reason for the bleeding should be determined before etonogestrel and ethinyl estradiol vaginal ring is used.

• Breast cancer (now or in the past or if suspected) or


• Cancer of the lining of the uterus, cervix or vagina (now or in the past) or


• Cancer that worsens when estrogen is present (now or in the past) or


• Confined to bed or inability to move for long period of time or


• Coronary artery disease (now or in the past) or


• Diabetes mellitus with blood vessel problems or


• Headache (severe) with changes in vision, loss of coordination, inability to move, numbness in arms or legs, or fainting or


• High blood pressure, severe or


• Jaundice while using birth control pills or


• Jaundice during pregnancy or


• Liver disease (active) or


• Liver tumors or


• Surgery (major) or


• Problems with circulation or blood clots, now or in the past, such as:


• Blood clots in your brain or


• Blood clots in your legs or


• Blood clots in your lungs or


• Blood clots in your eyes


• Problems with heart valves—These conditions may increase your chance of serious side effects.

• Coronary artery disease risk factors such as:


• Diabetes (sugar diabetes) or


• High blood pressure or


• High cholesterol or


• Obesity—These conditions may increase your chance of serious side effects when using etonogestrel and ethinyl estradiol vaginal ring.

• Depression or


• Diabetes mellitus (sugar diabetes) or


• Headache of type not experience before or


• High blood pressure or


• Kidney disease or


• Migraine headache or


• Problems with too much insulin in your blood or


• Problems with too much sugar in your blood—This medication may make this condition worse.

• Menstrual vaginal bleeding (lack of or heavy)—This problem may occur when contraceptive medicine is stopped, especially if it has happened in the past.

• Smoking cigarettes—Smoking may increase your chance of serious side effects, especially if you are over 35 years of age or smoke 15 cigarettes or more a day.

• Swollen ankles, feet, or hands—This medication may make this condition worse. ethinyl estradiol and etonogestrel may also make other medical problems worse when your body keeps too much water or fluid.

Proper Use of ethinyl estradiol and etonogestrel

This etonogestrel and ethinyl estradiol vaginal ring comes with patient information. You must understand this information. You should keep a copy for reference. Be sure you understand possible problems with the etonogestrel and ethinyl estradiol vaginal ring , especially side effects, risks, and signs of a serious problem.

It is important to know how and when to insert, remove, or replace etonogestrel and ethinyl estradiol vaginal ring. If you have any questions about this ask your doctor. It is very important to follow the instructions on when to insert and remove your etonogestrel and ethinyl estradiol vaginal ring.

Pregnancy must be ruled out if there is a problem or change in your regimen. It is important to use additional methods of contraception if there was a problem or change in the regimen. Back-up contraception must be used until the ring has been in place for seven days.

Dosing

The dose of ethinyl estradiol and etonogestrel will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of ethinyl estradiol and etonogestrel. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For vaginal dosage form
  
  • For preventing pregnancy:
    
    • Adults—One ring inserted into the vagina for three weeks. The ring is removed for a one week break and the old ring is disposed of. A new ring is inserted one week after the last ring was removed and left in place for three weeks. Note: The ring must be inserted on the appropriate day and left in place for three weeks. This means that the ring is removed three weeks later on the same day of the week it was inserted and at about the same time.
    
    
  
  

Missed Dose

Call your doctor or pharmacist for instructions.

If the etonogestrel and ethinyl estradiol vaginal ring has slipped out of the vagina and it has been out less than three hours, you should still be protected from pregnancy. If the etonogestrel and ethinyl estradiol vaginal ring has been out of the vagina for more than three hours you may not adequately be protected from pregnancy, and you must use an extra method of birth control until the etonogestrel and ethinyl estradiol vaginal ring has been in place for seven days in a row. For additional information changes or problems with your regimen consult your patient information leaflet or ask your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using ethinyl estradiol and etonogestrel

It is very important that your doctor check you at regular annual visits. Your doctor may want to see you more often than once a year.

It is very important that you tell your doctor if you think that you might be pregnant or if you miss a period.

This product does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

ethinyl estradiol and etonogestrel Side Effects

The risk of serious adverse effects is unlikely for most women using the etonogestrel and ethinyl estradiol vaginal ring. However, oral combination hormonal contraceptives have been associated with unwanted effects which may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not determined

• Abdominal fullness


• abdominal pain or tenderness usually after eating a meal


• blurred vision


• changes in skin color


• chest pain or discomfort


• confusion


• constipation


• diarrhea


• dizziness


• gaseous abdominal pain


• headache


• inability to speak


• nausea


• nervousness


• numbness of hands


• pain or discomfort in arms, jaw, back or neck


• pain


• pains in chest, groin, or legs, especially calves of legs


• pounding in the ears


• prominent superficial veins over affected area with tenderness and warmth


• recurrent fever


• seizures


• severe headaches of sudden onset


• shortness of breath


• slow or fast heartbeat


• sudden loss of coordination


• sudden onset of slurred speech


• sudden vision changes


• sudden and severe weakness in arm and/or leg on one side


• sweating


• swelling


• swelling of foot or leg on one side of the body


• temporary blindness


• vomiting or vomiting of blood


• yellow eyes or skin

Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur:

• Menstrual changes


• nausea


• vaginal bleeding


• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

• Cough


• fever


• headache


• itching of the vagina or genital area


• pain during sexual intercourse


• pain or tenderness around eyes and cheekbones


• sore throat


• stuffy or runny nose


• thick, white vaginal discharge with no odor or with a mild odor


• tightness of chest or wheezing


• weight gain

Less common

• Crying


• depersonalization


• false or unusual sense of well-being


• hoarseness


• mental depression


• paranoia


• quick to react or overreact emotionally


• rapidly changing moods, mild feeling of sadness or discouragement that come and go

Incidence not determined

• Absent, missed, or irregular menstrual periods


• bloody vaginal discharge


• brown, blotchy spots on exposed skin


• chills


• clay-colored stools


• contact lenses intolerance


• dark urine


• decreased amount or quality of milk


• dry mouth


• dry skin


• fatigue


• flushed


• fruit-like or unpleasant breath odor


• increased hunger


• increased thirst


• increased urination


• loss of appetite


• medium to heavy, irregular vaginal bleeding between regular monthly periods, which may require the use of a pad or a tampon


• rash


• soreness, swelling, or discharge from the breast or breasts


• trouble getting pregnant


• unexplained weight loss


• unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More ethinyl estradiol and etonogestrel Vaginal resources

• Ethinyl estradiol and etonogestrel Vaginal Use in Pregnancy & Breastfeeding
• Ethinyl estradiol and etonogestrel Vaginal Drug Interactions
• Ethinyl estradiol and etonogestrel Vaginal Support Group
• 236 Reviews for Ethinyl estradiol and etonogestrel Vaginal - Add your own review/rating

Compare ethinyl estradiol and etonogestrel Vaginal with other medications

• Birth Control

Mercaptopurina Refasa

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• Peru

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Ixor may be available in the countries listed below.

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Roxithromycin is reported as an ingredient of Ixor in the following countries:

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